Many years later, the brothers' father disappeared as well, triggering season 1’s often traumatic events.

The pilot episode ofSupernaturalshowed the origin story of the Winchester brothers and Dean’s bizarre lifestyle.

Thrown into a turbulent nightmare, the boys' mother,Mary, was horrifically murderedearly in episode 1.

Supernatural TV Series Poster

A nasty demonic home invasion left Mary with a fatal wound to the stomach, pinned to the ceiling.

This set a precedent for the brutality and inventiveness of episodes to come.

Jess was Sam’s long-term girlfriend and the cornerstone of his stable, normal life.

Supernatural Sam and Dean at faith healer’s church.

It was hard to see Jess go in the same way as Mary.

Unfortunately, Sam’s girlfriend was soon embroiled in the mystery and tragedy shrouding the Winchester family since birth.

It was hard to see Jess go in the same way as Mary.

Pishtaco from Supernatural with its tongue out, with a leviathan’s open mouth serving as the background

Created by Eric Kripke, Supernatural is a fantasy/drama series that premiered in 2005. The series follows the adventures of Dean and Sam Winchester - two men wronged by supernatural beings as children who now spend their days investigating and hunting demons, ghosts, and monsters across the United States.

Supernaturaldeveloped Crowley from an evil demon to a lovable rogue, to a genuine hero.

The writers' treatment of Sheppard is unfortunate because Crowley had become one ofSupernatural’sbest supporting characters.

Charlie was a fan favorite and a highlight of the show, exhibiting Day at her best.

Jensen Ackles as Dean and Alexander Calvert as Jack from Supernatural looking sad.

But it wasn’t to be.

This madeJo’s eventual death hit hard.

InSupernatural,Jo was played by Alona Tal and Ellen was played by Samantha Ferris.

Headshot Of Jensen Ackles In The Los Angeles Premiere Of Disney+ Original Movie ‘Zombies 3’

The two Harvelles wereabsolute heroes inSupernatural, and their deaths were a devastating payoff of one ofSupernatural’sbest seasons.

Ben was Lisa’s son, but may have also been Dean’s son.

This dream, which had seemed unobtainable, was within grasp.

Headshot Of Misha Collins IN The 2019 CW Upfront

Dean had never been more kind, powerful, and tragic.

Not only did Castiel confess his feelings, but doing so made him truly happy.

Misha Collins played angel Castiel inSupernaturalseasons 4 to 15.

Supernatural

It was this happiness that triggered the curse of the Empty, which arrived to collect Castiel as promised.

Tragedy was built into this curse at its core, swiping joy away the very second it became realized.

Important characters inSupernaturalgenerally developed very thick plot armor, dying multiple times and coming back to life.

ButBobby died, finally and resolutely, in episode 10of season 7.

This was an important plot development, but hard to stomach.

Indeed, seeing Dean and Sam return in aSupernaturalseason 16 would probably be welcomed by most fans.

After fifteen years of getting to know Dean inSupernatural, his death did feel like losing a brother.